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Embryonic Stem Cells

Products

PeptiMatrix™ Core

Available in a range of stiffnesses, PeptiMatrix™ Core can also be further customised by the end user with selected matrix proteins or glycosaminoglycans (GAGs) alongside your cells to build fully-defined in vitro environments.

PeptiMatrix™ Plus

PeptiMatrix™ Plus is

 designed to mimic collagen, the most abundant protein in the human extracellular matrix.

This product is now available for purchase! Click below to order...

 

PeptiMatrix™ RGD

PeptiMatrix™ RGD has been functionalised with a synthetic Arg-Gly-Asp (RGD) motif, perfect for modelling tissues rich in fibronectin.

This product is now available for purchase! Click below to order...

PeptiMatrix™ Prime

PeptiMatrix™ Prime will be a highly specialised and complex formulation of hydrogel designed to reflect the same complexity of hydrogels derived from EHS sarcoma, whilst being chemically defined and remaining 100% animal-product free.

PeptiMatrix™ IKVAV

PeptiMatrix™ IKVAV has been engineered to mimic tissues rich in laminin, by providing a synthetic IKVAV

(Ile-Lys-Val-Ala-Val) motif.

This product is now available for purchase! Click below to order...

Bespoke Hydrogels

Are you needing something more bespoke, perhaps requiring specific biochemical motifs or mechanical properties for your application or hardware?

 

Get in touch and we can design this for you!

Examples

Below are some key examples where researchers were able to leverage PeptiMatrix™ hydrogels to build more physiologically relevant models of development and disease.

 

Compatibility

Because PeptiMatrix™ is available in a range of different stiffnesses and customisation options, it can be used to create a variety of tissue mimics and is compatible across a range of different applications.

 

PeptiMatrix™ hydrogels have so been far validated across the following cell types:

We have also tested our technology for compatibility across multiple standard analytical assays, including:

  • Immunocytochemistry

  • Immunohistochemistry

    • Including embedding the hydrogels for sectioning

  • Fluorescent and luminescence readouts using a plate reader

    • Including standard cell viability assays

  • RNA and DNA extraction

  • Proteomic and Glycomic analysis

  • Bulk osscilitory rheology
  • Microrheology

    • Including optical trapping and AFM-based rheometry

Additionally, cells can be extracted in a cell-friendly manner for re-seeding or downstream processing, allowing greater compatibility with a variety of other standard assays.

Fully optimised Standard Operating Protocols (SOPs) for any of these, and more, are freely available by emailing info@peptimatrix.com.

Pricing

*Values provided are indicative, and were evaluated by bulk osscilitory rheology after incubation in DMEM medium for 24 h. Other methods of measuring stiffness may yield different results. For full details, email info@peptimatrix.com.

We can also offer discounts if ordering in bulk or for repeat orders.

Don't see your desired tissue stiffness or customisation option in the table above?

Get in touch, and we can work with you to design a bespoke hydrogel that fits your specific requirements.

Request a Quote

If you would like to request a quote, or would simply like to learn more about our technology, please get in touch!

PeptiMatrix Limited,

Biodiscovery Institute,

Science Road,
University of Nottingham,

NG7 2RD, UK

E: info@peptimatrix.com

T: +44 (0) 7599 442871

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