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Embryonic Stem Cells

Products

PeptiMatrix™ Core

Available in a range of stiffnesses, PeptiMatrix™ Core can also be further customised by the end user with selected matrix proteins or glycosaminoglycans (GAGs) alongside your cells to build fully-defined in vitro environments.

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PeptiMatrix™ Plus

PeptiMatrix™ Plus is designed to mimic collagen, by providing the α1β1, α2β1, α5β1, and av-class integrin binding domains of Col I & IV

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PeptiMatrix™ RGD

PeptiMatrix™ RGD has been functionalised with a synthetic Arg-Gly-Asp (RGD) motif, perfect for modelling tissues rich in fibronectin.

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PeptiMatrix™ Prime

PeptiMatrix™ Prime will be a highly specialised and complex formulation of hydrogel designed to reflect the same complexity of hydrogels derived from EHS sarcoma, whilst being chemically defined and remaining 100% animal-product free.

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PeptiMatrix™ IKVAV

PeptiMatrix™ IKVAV has been engineered to mimic tissues rich in laminin, by providing a synthetic IKVAV

(Ile-Lys-Val-Ala-Val) motif.

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Bespoke Hydrogels

Are you needing something more bespoke, perhaps requiring specific biochemical motifs or mechanical properties for your application or hardware?

 

Get in touch and we can design this for you!

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Compatibility

Because PeptiMatrix™ is available in a range of different stiffnesses and customisation options, it can be used to create a variety of tissue mimics and is compatible across a range of different applications.

 

PeptiMatrix™ hydrogels have so been far validated across the following cell types:

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✓ - Validated ; ✓✓ - Our recommendation

We have also tested our technology for compatibility across multiple standard set-up and end-point assays, including:

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  • Cell encapsulation (3D)

  • Well-plate coating ("2.5D")

  • LIVE/DEAD cell viability assay

  • CellTiter-Glo 3D cell viability assay
  • PrestoBlue cell viability assay
  • RNA extraction
  • Bulk osscilitory rheology
  • Microrheology (e.g., AFM)
  • Proteomic & Glycomic analsysis
  • Embeeding and sectioning for IHC
  • Immunostaining with antibodies (ICC)

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Additionally, cells can be extracted in a cell-friendly manner for re-seeding or downstream processing, allowing greater compatibility with a variety of other standard assays.

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Fully optimised Standard Operating Protocols (SOPs) for many of these are freely available to download from our Knowledge Base. If you require information or guidance on a protocol not listed there, please email info@peptimatrix.com.

Pricing

*Values provided are indicative, and were evaluated by bulk osscilitory rheology after incubation in DMEM medium for 24 h. Other methods of measuring stiffness may yield different results. For full details, email info@peptimatrix.com.

Prices are in GBP and exclude VAT and delivery. A fully copy of our terms of sale are available upon request by emailing: info@peptimatrix.com

We also offer a PeptiMatrix™ Starter Kit, which includes 3 mL each of PMCORE100, PMCORE125, and PMCORE150 for just £550.00. This kit is ideal for evaluating how your cells respond to different matrix stiffnesses, helping you select the optimal one for your research.

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We can also offer tailored pricing for academic customers.

 

To request your tailored quote: info@peptimatrix.com

 

Request a Quote

If you would like to request a quote, or would simply like to learn more about our technology, please get in touch!

PeptiMatrix Limited,

Biodiscovery Institute,

Science Road,
Nottingham,

NG7 2RD, UK

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E: info@peptimatrix.com

T: +44 (0) 7599 442871

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